Dr Antonios Georgantzoglou

My project focuses on the investigation of how chemoattractant gradients are interpreted by migrating leukocytes in vivo. Research Associate Office Phone: +44 (0) 1223 768083 Research Interests My general interest lies in the quantitative investigation of cell dynamics and the development of image processing tools for this purpose. My current research project focuses on leukocyte migration, stimulated by chemoattractants. Recent in vivo studies have shown that these cells alter their speed as they move closer to a source of chemoattractant. Through in vivo imaging in zebrafish and by developing image analysis algorithms, I am studying the driving force behind this leukocyte mobilisation, which is driven by actin dynamics (Video 1). To induce directed leukocyte migration I use assays developed in the Sarris lab such as laser wounding, local bacterial injections…

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