PLOS ECR Community

Progress in science depends on new techniques, new discoveries, and new ideas, probably in that order. – Sydney Brenner In 2012, my former research mentor and principal investigator Rafael Yuste published a paper with his colleagues proposing the Brain Activity Map (BAM) Project. Little did we know that this project would be taken up by the Obama Administration in 2013 and transformed into the Brain Research Advancing through Innovative Neurotechnologies (BRAIN) Initiative. The basic principle of the BAM Project is to understand how the coordinated activity of large numbers of neurons leads to complex behaviors, we must first characterize all these neurons and reconstruct a full record of their neural activity. In order to do so, Professor Yuste and his colleagues believed large-scale, international collaboration was necessary. Their idea caught on…

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