Searching for a cure to HIV

Approximately two miles north of Main Campus on North Broad Street, researchers at the Lewis Katz School of Medicine took another step in the fight against HIV.The research team, led by Dr. Kamel Khalili—who chairs the neuroscience department—uses a gene-editing technology it developed to snip the virus out of cells. This month, the technique successfully stopped HIV-1 virus replication in the T-cells of blood from HIV-positive patients. “I think it’s a very [big] first step toward the strategy which can be developed toward [the] cure,” Khalili said. Dr. Wenhui Hu, an associate professor in neuroscience, said because HIV has “been integrated into the host cell,” the gene-editing technology is the best way to eliminate any further spread of the virus. “Once the virus infects, the viral genome integrates into the…

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