Francesco Carlo Morabito* Maurizio Campolo* Nadia Mammone∥ Mario Versaci* Silvana Franceschetti† Fabrizio Tagliavini† Vito Sofia‡ Daniela Fatuzzo‡ Antonio Gambardella§ Angelo Labate§ Laura Mumoli§ Giovanbattista Gaspare Tripodi¶ Sara Gasparini§, ¶ Vittoria Cianci¶ Chiara Sueri¶ Edoardo Ferlazzo§, ¶ Umberto Aguglia§, ¶ *University Mediterranea of Reggio Calabria, Italy †Neurologic Institute “Carlo Besta”, Milan, Italy ‡Institute of Neurology, University of Catania, Italy §Magna Græcia University, Catanzaro, Italy ¶Regional Epilepsy Centre, Bianchi-Melacrino-Morelli Hospital, Reggio Calabria, Italy ∥IRCCS Centro Neurolesi Bonino-Pulejo, Via Palermo c/da Casazza, SS. 113, Messina, Italy A novel technique of quantitative EEG for differentiating patients with early-stage Creutzfeldt–Jakob disease (CJD) from other forms of rapidly progressive dementia (RPD) is proposed. The discrimination is based on the extraction of suitable features from the time-frequency representation of the EEG signals through continuous wavelet transform (CWT).…

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